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Your administrative user account needs the Endpoint Protection Manager security role.Clients using an OS listed in the Supported client operating systems section below.Clients computers running the Configuration Manager client.Subscription to the Microsoft Defender for Endpoint online service.Microsoft Defender for Endpoint is supported on PCs running the Configuration Manager client or managed by Microsoft Intune. By adding and deploying a client onboarding configuration file, Configuration Manager can monitor deployment status and Microsoft Defender for Endpoint agent health. Microsoft Defender for Endpoint's cloud-based portal is Microsoft Defender Security Center. Configuration Manager policies can help you onboard and monitor Windows 10 or later clients. Microsoft Defender for Endpoint helps enterprises detect, investigate, and respond to advanced attacks on their networks. Applies to: Configuration Manager (current branch)Įndpoint Protection can help manage and monitor Microsoft Defender for Endpoint.